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Site-specific analysis of B-cell non-Hodgkin’s lymphomas of the head and neck: A retrospective 10-year observation.
- Source :
- Acta Oto-Laryngologica; Nov2015, Vol. 135 Issue 11, p1168-1171, 4p
- Publication Year :
- 2015
-
Abstract
- Conclusion:B-cell non-Hodgkin’s lymphoma (B-NHL) in the head and neck most commonly affected the oropharynx and the cervical lymph node in sexagenarian patients, with more than 70% of these cases being diffuse large B-cell lymphoma (DLBCL). Accordingly, B-NHL should be considered one of the most important differential diagnoses of head and neck malignancies.Objectives:It has previously been reported that the majority of head and neck malignant lymphomas are B-NHLs. This analysis aimed to assess the site-specific profiles of B-NHL of the head and neck.Methods:The medical records of patients with B-NHL of the head and neck diagnosed between January 2004 and December 2013 were retrospectively reviewed. The clinical parameters of these patients, including age, sex, site distribution, and histopathologic sub-type, were analyzed.Results:A total of 153 cases (95 males; 58 females) were included in this analysis (male-to-female ratio = 1.64:1). The patient age at the time of diagnosis ranged from 30–92 years (median = 68 years). The oropharynx was the most commonly affected site (40.5%), followed by the cervical lymph nodes (33.3%). The most common histopathologic sub-type was DLBCL (71.9%), followed by follicular lymphoma (11.1%), and extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (9.2%). [ABSTRACT FROM PUBLISHER]
Details
- Language :
- English
- ISSN :
- 00016489
- Volume :
- 135
- Issue :
- 11
- Database :
- Complementary Index
- Journal :
- Acta Oto-Laryngologica
- Publication Type :
- Academic Journal
- Accession number :
- 109966960
- Full Text :
- https://doi.org/10.3109/00016489.2015.1061700