Back to Search
Start Over
Diagnostic accuracy of diffusion-weighted MRI for differentiation of cervical cancer and benign cervical lesions at 3.0T: Comparison with routine MRI and dynamic contrast-enhanced MRI.
- Source :
- Journal of Magnetic Resonance Imaging; Oct2015, Vol. 42 Issue 4, p1094-1099, 6p
- Publication Year :
- 2015
-
Abstract
- <bold>Purpose: </bold>To compare the diagnostic accuracy of routine magnetic resonance imaging (MRI) (T1 WI and T2 WI), diffusion-weighted MRI (DWI), and DCE-MRI (dynamic contrast-enhanced MRI) at 3.0T for differentiation of cervical cancer and benign cervical lesions.<bold>Materials and Methods: </bold>A cohort of 75 cervical cancer patients, 26 cervical leiomyoma patients, 22 patients with cervical polyps consecutively underwent pelvic MRI scanning on a 3T MR unit. Two radiologists independently evaluated images at three imaging settings; routine MRI alone, DWI combined with routine MRI (DWI+routine MRI), and DCE-MRI. The apparent diffusion coefficients (ADCs) were calculated from b 0, 600 s/mm(2) and b 0, 1000 s/mm(2).<bold>Results: </bold>DWI+routine MRI was significantly better than routine MRI and obtained high accuracy (0.95); the diagnostic performance was not significantly different between DWI+routine MRI and DCE-MRI. Reader agreement was excellent for both DWI+routine MRI (κ, 0.90) and DCE-MRI (κ, 0.92). The ADCs of cervical cancer were significantly lower than those of benign cervical lesions at both ADC maps (P = 0.0001). The diagnostic accuracy was not different at both ADC maps (P = 0.375).<bold>Conclusion: </bold>For differentiation of cervical cancer and benign cervical lesions, unenhanced MRI with combined diffusion-weighted and routine MRI (DWI+routine MRI) at 3T can provide accurate information and may be preferable to DCE. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10531807
- Volume :
- 42
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Journal of Magnetic Resonance Imaging
- Publication Type :
- Academic Journal
- Accession number :
- 109467037
- Full Text :
- https://doi.org/10.1002/jmri.24894