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An Organocatalytic Access to Spiro[4.5]decanes and Spiro[4.6]undecanes Containing Aminolactones and 3-Aminopyrrolidines.
- Source :
- Synthesis; 2015, Vol. 47 Issue 17, p2549-2553, 5p
- Publication Year :
- 2015
-
Abstract
- The organocatalyzed Mannich coupling of cyclic carboxaldehydes allowed the concise and simple preparation of spirocyclic aminolactones. Their conversion into pharmaceutically relevant spiro[4.5]cyclic and spiro[4.6]cyclic 3-aminopyrrolidines is also described. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00397881
- Volume :
- 47
- Issue :
- 17
- Database :
- Complementary Index
- Journal :
- Synthesis
- Publication Type :
- Academic Journal
- Accession number :
- 109032167
- Full Text :
- https://doi.org/10.1055/s-0034-1380146