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Micro-CT analyses of historical bone samples presenting with osteomyelitis.
- Source :
- Skeletal Radiology; Oct2015, Vol. 44 Issue 10, p1507-1514, 8p
- Publication Year :
- 2015
-
Abstract
- Objective: Osteomyelitis is an inflammation of the bone marrow mainly caused by bacteria such as Staphylococcus aureus. It typically affects long bones, e.g. femora, tibiae and humeri. Recently micro-computed tomography (μCT) techniques offer the opportunity to investigate bone micro-architecture in great detail. Since there is no information on long bone microstructure in osteomyelitis, we studied historic bone samples with osteomyelitis by μCT. Materials and methods: We investigated 23 femora of 22 individuals suffering from osteomyelitis provided by the Collection of Anatomical Pathology, Museum of Natural History, Vienna (average age 44 ±19 years); 9 femora from body donors made available by the Department of Applied Anatomy, Medical University of Vienna (age range, 56-102 years) were studied as controls. Bone microstructure was assessed by μCT VISCOM X 8060 II with a minimal resolution of 18 μm. Results: In the osteomyelitic femora, most prominent alterations were seen in the cortical compartment. In 71.4 % of the individuals with osteomyelitis, cortical porosity occurred. 57.1 % of the individuals showed cortical thinning. In 42.9 % trabecularisation of cortical bone was observed. Conclusion: Osteomyelitis is associated with severe alterations of cortical bone structure otherwise typically observed at old age such as cortical porosity and cortical thinning. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 03642348
- Volume :
- 44
- Issue :
- 10
- Database :
- Complementary Index
- Journal :
- Skeletal Radiology
- Publication Type :
- Academic Journal
- Accession number :
- 108931497
- Full Text :
- https://doi.org/10.1007/s00256-015-2203-8