The association of diet and other lifestyle factors with the onset of overactive bladder: a longitudinal study in men.

<bold>Objective: </bold>To investigate associations between diet and non-dietary lifestyle factors and the onset of overactive bladder (OAB) in men.<bold>Subjects: </bold>Random sample of community-dwelling men aged 40 years plus.<bold>Design and Methods: </bold>Baseline data on urinary symptoms and diet were collected from 5454 men using a postal questionnaire and a food-frequency questionnaire. Follow-up data on urinary symptoms were collected from 4887 men in a postal survey one year later. Logistic regression analysis was used to investigate diet and lifestyle factors associated with onset of OAB in the men without OAB at baseline.<bold>Results: </bold>There was a highly significant negative association between beer intake at baseline and subsequent OAB onset (P=0.001), with reduced risk at all levels of intake compared with those who seldom/never drank beer. Adjustment for total alcohol intake (g ethanol day(-1)) reduced the significance of the association (P=0.02). None of the food groups studied was associated with OAB onset, with the possible exception of potatoes (P=0.05), which showed an increased risk of onset at the highest level of consumption. Physical activity, smoking and obesity were not significantly associated.<bold>Conclusions: </bold>While most diet and lifestyle factors were not associated with OAB onset, the evidence from this prospective longitudinal study suggests that beer may have a protective role in the development of OAB. This could be due to a non-alcoholic ingredient as well as the alcohol content. [ABSTRACT FROM AUTHOR]