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Science. Biomarkers of myocardial infarction in patients undergoing gastrointestinal cancer surgery.
- Source :
- Laboratory Medicine; Feb2009, Vol. 40 Issue 2, p91-95, 5p
- Publication Year :
- 2009
-
Abstract
- Objective: The evaluation of innovative biomarkers of myocardial damage in the perioperative period.Methods: Twenty-four patients with gastric or colorectal cancer were studied and samples were collected for the measurement of myoglobin, troponin I (cTnI), creatine kinase isoenzyme MB (CK-MB), glycogen phosphorylase isoenzyme BB (GPBB), carbonic anhydrase III (CA III), fatty acid-binding protein (FABP), and CK presurgery and on the first, seventh, and thirtieth days post-surgery.Results: Troponin I values were unchanged throughout the study period. Myoglobin, GPBB, CA III, and FABP were significantly increased on day 1 after surgery. On the seventh day, GPBB, myoglobin, and FABP were still increased, whereas CK was decreased. Thirty days after surgery no significant variations were observed except a decrease of CK and CA III.Conclusions: These results show cTnI and CK-MB are unaffected by surgery, while the measurement of CA III, FABP, GPBB, and myoglobin might be unsuitable for diagnosing an acute coronary syndrome perioperatively. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00075027
- Volume :
- 40
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Laboratory Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 105641388
- Full Text :
- https://doi.org/10.1309/lm1wipccvs9jmdza