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Percutaneous cementoplasty in multiple myeloma: a valuable adjunct for pain control and ambulation maintenance.

Authors :
Tran Thang NN
Abdo G
Martin JB
Seium-Neberay Y
Yilmaz H
Verbist MC
Rufenacht D
Sappino AP
Dietrich PY
Tran Thang, Nhu Nam
Abdo, German
Martin, Jean-Baptiste
Seium-Neberay, Yodit
Yilmaz, Hasan
Verbist, Marie-Christine
Rufenacht, Daniel
Sappino, Andre-Pascal
Dietrich, Pierre-Yves
Source :
Supportive Care in Cancer; Aug2008, Vol. 16 Issue 8, p891-896, 6p
Publication Year :
2008

Abstract

<bold>Goals Of Work: </bold>Bone pain and functional impairment are major concerns for multiple myeloma (MM) patients. The goal of this study was to better define the role of percutaneous cementoplasty (PC) in improving their quality of life.<bold>Materials and Methods: </bold>This retrospective analysis included 28 consecutive heavily pretreated MM patients managed at our institution between 1996 and 2002. They underwent a total of 34 PC procedures for the treatment of 117 vertebrae and 2 iliac sites and were evaluated at 1 month.<bold>Main Results: </bold>Significant pain reduction of >50% was obtained after 83% of the procedures, with a mean visual analogous score decreasing from 7.48/10 to 2.1/10 (p < 0.001). It resulted in a complete interruption of opiate analgesic consumption after 59.3% of the procedures, with a mean decrease of 70.4% in the opiate dose. Functional impairment was evaluated with the Eastern Cooperative Oncology Group (ECOG) performance status scale, with mean scores improving from 1.9 to 0.86 after the procedures (p = 0.001). There was no major complication.<bold>Conclusion: </bold>PC is a safe, feasible, and efficient approach for the treatment of bone pain and disability in MM patients. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09414355
Volume :
16
Issue :
8
Database :
Complementary Index
Journal :
Supportive Care in Cancer
Publication Type :
Academic Journal
Accession number :
105552911
Full Text :
https://doi.org/10.1007/s00520-007-0344-6