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Incidence, mortality and survival patterns of prostate cancer among residents in Singapore from 1968 to 2002.

Authors :
Chia SE
Tan CS
Lim GH
Sim X
Pawitan Y
Reilly M
Mohamed Ali S
Lau W
Chia KS
Chia, Sin Eng
Tan, Chuen Seng
Lim, Gek Hsiang
Sim, Xueling
Pawitan, Yudi
Reilly, Marie
Mohamed Ali, Safiyya
Lau, Weber
Chia, Kee Seng
Source :
BMC Cancer; 2008, Vol. 8, p368-368, 1p
Publication Year :
2008

Abstract

<bold>Background: </bold>From 1968 to 2002, Singapore experienced an almost four-fold increase in prostate cancer incidence. This paper examines the incidence, mortality and survival patterns for prostate cancer among all residents in Singapore from 1968 to 2002.<bold>Methods: </bold>This is a retrospective population-based cohort study including all prostate cancer cases aged over 20 (n = 3613) reported to the Singapore Cancer Registry from 1968 to 2002. Age-standardized incidence, mortality rates and 5-year Relative Survival Ratios (RSRs) were obtained for each 5-year period. Follow-up was ascertained by matching with the National Death Register until 2002. A weighted linear regression was performed on the log-transformed age-standardized incidence and mortality rates over period.<bold>Results: </bold>The percentage increase in the age-standardized incidence rate per year was 5.0%, 5.6%, 4.0% and 1.9% for all residents, Chinese, Malays and Indians respectively. The percentage increase in age-standardized mortality rate per year was 5.7%, 6.0%, 6.6% and 2.5% for all residents, Chinese, Malays and Indians respectively. When all Singapore residents were considered, the RSRs for prostate cancer were fairly constant across the study period with slight improvement from 1995 onwards among the Chinese.<bold>Conclusion: </bold>Ethnic differences in prostate cancer incidence, mortality and survival patterns were observed. There has been a substantial improvement in RSRs since the 1990s for the Chinese. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14712407
Volume :
8
Database :
Complementary Index
Journal :
BMC Cancer
Publication Type :
Academic Journal
Accession number :
105530906
Full Text :
https://doi.org/10.1186/1471-2407-8-368