Coprevalence of tremor with spasmodic dysphonia: a case-control study.

<bold>Objectives/hypothesis: </bold>The aim of this study was to define the coprevalence of tremor with spasmodic dysphonia (SD).<bold>Study Design: </bold>A single-institution, prospective, case-control study was performed from May 2010 to July 2010.<bold>Methods: </bold>Consecutive patients with SD (cases) and other voice disorders (controls) were enrolled prospectively. Each participant underwent a voice evaluation and an evaluation for tremor.<bold>Results: </bold>There were 146 voice disorder controls and 128 patients with SD enrolled. Of patients with SD 26% had vocal tremor, 21% had nonvocal tremor. Patients with SD were 2.8 times more likely to have coprevalent tremor than the control group (odds ratio = 2.81; 95% confidence interval, 1.55-5.08), and only 35% of patients with SD had been seen by a neurologist for the evaluation of dystonia and tremor.<bold>Conclusions: </bold>Tremor is highly prevalent in patients with SD. It is important for each patient diagnosed with SD to undergo an evaluation for tremor, and this is especially important in patients diagnosed with vocal tremor. [ABSTRACT FROM AUTHOR]