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Aromatic Nitro Groups and Their Reactions with Chelated Ester Enolates.

Authors :
Stolz, Daniel
Kazmaier, Uli
Pick, Rigobert
Source :
Synthesis; 2006, Vol. 2006 Issue 19, p3341-3347, 7p
Publication Year :
2006

Abstract

Chelated amino acid ester enolates react with aromatic nitro compounds in a 1,3-addition mode at the nitro group giving amino acids bearing an aryl(hydroxy)amino side chain. Best results were obtained with trifluoroacetyl-protected glycinates. Two equivalents of enolate are necessary for complete conversion, because one equivalent is oxidized during the reaction. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00397881
Volume :
2006
Issue :
19
Database :
Complementary Index
Journal :
Synthesis
Publication Type :
Academic Journal
Accession number :
103536189
Full Text :
https://doi.org/10.1055/s-2006-950228