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Effect of multivitamin supplements on weight gain during pregnancy among HIV-negative women in Tanzania.
- Source :
- Maternal & Child Nutrition; Jul2015, Vol. 11 Issue 3, p297-304, 8p
- Publication Year :
- 2015
-
Abstract
- Multivitamin supplementation has been shown to reduce the risk of low birthweight. This effect could be mediated through gestational weight gain. However, the effect of multivitamin supplementation on weight gain during pregnancy has not been fully studied. The objective of this study was to examine the effects of multivitamins on pregnancy weight gain. We enrolled 8468 HIV-negative women from Dar es Salaam, Tanzania, in a randomised, placebo-controlled trial of multivitamins on birth outcomes. Women were randomly assigned to receive either a daily oral dose of multivitamin tablets or a placebo and were weighed every 4 weeks from enrolment until the last visit before delivery. Intent-to-treat analyses were carried out to examine the effects of multivitamins on pregnancy weight gain. Multivariate linear and binomial regression models with the log-link function were used to examine the association of weight gain during pregnancy to birthweight. The overall total weight gain was 253 g ( SE: 69, P: 0.0003) more, while the overall 4 weekly weight gain was 59 g greater ( SE: 18, P: 0.005) among women who received multivitamins compared to placebo. Women in the lowest quartile of gestational weight gain had babies with an average birthweight of 3030 g ( SD: 524), while women in the highest quartile had babies weighing 3246 g ( SD: 486), on average. Prenatal multivitamin supplements increased gestational weight gain, which was a significant predictor of birthweight. [ABSTRACT FROM AUTHOR]
- Subjects :
- BIRTH weight
CHI-squared test
CONFIDENCE intervals
DIETARY supplements
GESTATIONAL age
HIV infections
EVALUATION of medical care
MOTHERS
MULTIVARIATE analysis
DURATION of pregnancy
REGRESSION analysis
RESEARCH funding
STATISTICAL sampling
STATISTICS
VITAMINS
WEIGHT gain
DATA analysis
BODY mass index
RANDOMIZED controlled trials
RELATIVE medical risk
REPEATED measures design
BLIND experiment
DATA analysis software
DESCRIPTIVE statistics
KRUSKAL-Wallis Test
PREGNANCY
Subjects
Details
- Language :
- English
- ISSN :
- 17408695
- Volume :
- 11
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Maternal & Child Nutrition
- Publication Type :
- Academic Journal
- Accession number :
- 103380553
- Full Text :
- https://doi.org/10.1111/mcn.12018