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Does Pet-Keeping Modify the Association of Delivery Mode with Offspring Body Size?
- Source :
- Maternal & Child Health Journal; Jun2015, Vol. 19 Issue 6, p1426-1433, 8p
- Publication Year :
- 2015
-
Abstract
- Caesarean-section (CS) delivery increases risk of childhood obesity, and is associated with a distinct early-life gut microbiome, which may contribute to obesity. Household pets may alter human gut microbiome composition. We examined if pet-keeping modified the association of CS with obesity at age 2 years in 639 Wayne County Health, Environment, Allergy and Asthma Longitudinal Study birth cohort participants. Pet-keeping was defined as having a dog or cat (indoors ≥1 h/day) at child age 2 years. We used logistic regression to test for an interaction between CS and pet-keeping with obesity (BMI ≥ 95th percentile) at age 2 years, adjusted for maternal obesity. A total of 328 (51.3 %) children were male; 367 (57.4 %) were African American; 228 (35.7 %) were born by CS; and 55 (8.6 %) were obese. After adjusting for maternal obesity, CS-born children had a non-significant ( P = 0.25) but elevated 1.4 (95 % CI 0.8, 2.5) higher odds of obesity compared to those born vaginally. There was evidence of effect modification between current pet-keeping and delivery mode with obesity at age 2 years (interaction P = 0.054). Compared to children born vaginally without a pet currently in the home, children born via CS without a pet currently in the home had a statistically significant ( P = 0.043) higher odds (odds ratio 2.00; 95 % CI 1.02, 3.93) of being obese at age 2 years. Pets modified the CS-BMI relationship; whether the underlying mechanism is through effects on environmental or gut microbiome requires specific investigation. [ABSTRACT FROM AUTHOR]
- Subjects :
- DIGESTIVE organ microbiology
RISK of childhood obesity
OBESITY complications
CESAREAN section
CHI-squared test
CONFIDENCE intervals
DELIVERY (Obstetrics)
PETS
QUESTIONNAIRES
REGRESSION analysis
RESEARCH funding
T-test (Statistics)
VAGINA
LOGISTIC regression analysis
BODY mass index
ODDS ratio
CHILDREN
PREGNANCY
Subjects
Details
- Language :
- English
- ISSN :
- 10927875
- Volume :
- 19
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- Maternal & Child Health Journal
- Publication Type :
- Academic Journal
- Accession number :
- 102883412
- Full Text :
- https://doi.org/10.1007/s10995-014-1649-y