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Pouched Mitral Isthmus Is Associated with Incomplete Linear Block in Atrial Fibrillation Patients with Mechanical Mitral Valve Replacement.
- Source :
- Journal of Cardiovascular Electrophysiology; May2015, Vol. 26 Issue 5, p501-508, 8p
- Publication Year :
- 2015
-
Abstract
- Pouched Mitral Isthmus and Ablation Block Background Previous studies have described the impact of mitral isthmus (MI) anatomy on the likelihood of achieving MI linear block in patients with native mitral valves (NMV) who underwent atrial fibrillation (AF) ablation. However, none have investigated that issue in AF patients with mechanical mitral valve replacements (MMVR). Methods and Results Twenty-nine consecutive patients who developed symptomatic persistent AF post-MMVR and referred for ablation were enrolled. Twenty-nine patients with NMV who underwent ablation of persistent AF during the same period were matched. With preprocedural cardiac computed tomographic imaging, MI anatomical features of all the participants were analyzed. Pouched MI was observed in 19 (65.5%) MMVR patients versus to 6 (20.7%) controls (P = 0.001). Bidirectional linear block across MI was achieved in 21 (72.4%) MMVR patients and 22 (75.9%) in the controls (P = 0.764). In the multivariable analysis, pouched MI was an independent predictor of incomplete MI block. Conclusions Pouched MI accounts for the majority of AF patients with MMVR and may be associated with incomplete bidirectional linear block of MI. [ABSTRACT FROM AUTHOR]
- Subjects :
- ATRIAL fibrillation treatment
DISEASE relapse
ACADEMIC medical centers
CATHETER ablation
CHI-squared test
COMPUTED tomography
CONFIDENCE intervals
ELECTROCARDIOGRAPHY
ELECTROPHYSIOLOGY
FISHER exact test
PROSTHETIC heart valves
LONGITUDINAL method
MITRAL valve
RESEARCH funding
SURVIVAL analysis (Biometry)
T-test (Statistics)
LOGISTIC regression analysis
TREATMENT effectiveness
DESCRIPTIVE statistics
ODDS ratio
MANN Whitney U Test
DIAGNOSIS
Subjects
Details
- Language :
- English
- ISSN :
- 10453873
- Volume :
- 26
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- Journal of Cardiovascular Electrophysiology
- Publication Type :
- Academic Journal
- Accession number :
- 102602794
- Full Text :
- https://doi.org/10.1111/jce.12649