Puberty in females enhances the risk of an outcome of multiple sclerosis in children and the development of central nervous system autoimmunity in mice.

Authors :: Ahn, Jeeyoon Jennifer
O’Mahony, Julia
Moshkova, Marina
Hanwell, Heather E
Singh, Hargurinder
Zhang, Monan Angela
Marrie, Ruth Ann
Bar-Or, Amit
Sadovnick, Dessa A
Dunn, Shannon E
Banwell, Brenda L
Source :: Multiple Sclerosis Journal; May2015, Vol. 21 Issue 6, p735-748, 14p
Publication Year :: 2015
Abstract: The article discusses a study regarding the female puberty-enhanced risk of multiple sclerosis (MS) in children and central nervous system (CNS) autoimmunity in mice. Topics discussed include experimental autoimmune encephalomyelitis (EAE), acquired demyelinating syndromes (ADS), and the use of brain magnetic resonance imaging (MRI).

Subjects :: PUBERTY
MULTIPLE sclerosis
AUTOIMMUNITY
ENCEPHALOMYELITIS
CHILDREN'S health
MAGNETIC resonance imaging
LABORATORY mice

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