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The Effect of Collagen Cross-Linking Procedure on the Material of Intracorneal Ring Segments.
- Source :
- Current Eye Research; Jun2015, Vol. 40 Issue 6, p592-597, 6p
- Publication Year :
- 2015
-
Abstract
- Purpose: To assess the potential impact of corneal crosslinking treatment (365 nm ultraviolet (UV)A irradiation with riboflavin) on the material properties of Intracorneal Rings Segments (ICRS). Materials and methods: Material properties were studied using FT-IR spectroscopy and UV-Vis spectroscopy. Rings were examined: (1) after installation of riboflavin solution, (2) after irradiation with UV-A light and (3) after instillation of riboflavin solution followed by instillation and coeval irradiation. The experiments followed the standard corneal cross-linking (CXL) protocol of corneal crosslinking treatment. Results: After instillation of riboflavin solution, a permanent intense yellow staining of the samples was observed. UV-Vis spectroscopy confirmed that a certain amount of riboflavin solution was absorbed into the samples after CXL procedure. FT-IR spectroscopic analysis showed alterations in the spectra of ICRS mainly at the 2800-3200 cm<superscript>−1</superscript> spectral region [modification in band intensities of CH<subscript>2</subscript> (2925 cm<superscript>−1</superscript>) and CH<subscript>3</subscript> (2950 cm<superscript>−1</superscript>)]. Conclusions: Our results suggest crosslinking reaction in ICRS material. This should be taken into consideration prior to any CXL treatment of post ICRS-implanted cornea. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 02713683
- Volume :
- 40
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- Current Eye Research
- Publication Type :
- Academic Journal
- Accession number :
- 102289061
- Full Text :
- https://doi.org/10.3109/02713683.2014.941071