Cortical thickness and surface area relate to specific symptoms in early relapsing–remitting multiple sclerosis.

The article presents a study which aims to investigate the difference in cortical surface area, thickness and volume between early relapsing-remitting multiple sclerosis (RRMS) patients and healthy controls and explores the relationship between such measures and neurological disability, fatigue and depression. It notes the magnetic resonance imaging (MRI), neurological and neuropsychological examinations underwent by RRMS patients. It reveals that cortical thickness is affected in early RRMS.