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NeuO: a Fluorescent Chemical Probe for Live Neuron Labeling.

Authors :
Er, Jun Cheng
Leong, Cheryl
Teoh, Chai Lean
Yuan, Qiang
Merchant, Paolomi
Dunn, Matthew
Sulzer, David
Sames, Dalibor
Bhinge, Akshay
Kim, Dongyoon
Kim, Seong-Min
Yoon, Myung-Han
Stanton, Lawrence W.
Je, Shawn H.
Yun, Seong-Wook
Chang, Young-Tae
Source :
Angewandte Chemie; Feb2015, Vol. 127 Issue 8, p2472-2476, 5p
Publication Year :
2015

Abstract

To address existing limitations in live neuron imaging, we have developed NeuO, a novel cell-permeable fluorescent probe with an unprecedented ability to label and image live neurons selectively over other cells in the brain. NeuO enables robust live neuron imaging and isolation in vivo and in vitro across species; its versatility and ease of use sets the basis for its development in a myriad of neuronal targeting applications. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00448249
Volume :
127
Issue :
8
Database :
Complementary Index
Journal :
Angewandte Chemie
Publication Type :
Academic Journal
Accession number :
100953347
Full Text :
https://doi.org/10.1002/ange.201408614