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‘Switch-off’ biosensing for chymotrypsin-catalyzed reaction by SPR–SERS spectroscopy.

Authors :
Fu, Cuicui
Xu, Weiqing
Chen, Gang
Xu, Shuping
Source :
Analyst; 2013, Vol. 138 Issue 21, p6282-6286, 5p
Publication Year :
2013

Abstract

We describe a novel ‘switch-off’ biosensing strategy for the detection of chymotrypsin based on surface plasmon resonance (SPR) and surface-enhanced Raman scattering (SERS) spectroscopy. This approach analyzes the fingerprint spectrum of the chymotrypsin-catalyzed substrate. The lowest probed concentration is 0.4 nM for chymotrypsin. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00032654
Volume :
138
Issue :
21
Database :
Complementary Index
Journal :
Analyst
Publication Type :
Academic Journal
Accession number :
100866716
Full Text :
https://doi.org/10.1039/c3an01427d