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Breast cancer risk reduction - is it feasible to initiate a randomised controlled trial of a lifestyle intervention programme (ActWell) within a national breast screening programme?
- Source :
- International Journal of Behavioral Nutrition & Physical Activity; 2014, Vol. 11, p1-30, 30p, 1 Diagram, 13 Charts
- Publication Year :
- 2014
-
Abstract
- Background Breast cancer is the most commonly diagnosed cancer and the second cause of cancer deaths amongst women in the UK. The incidence of the disease is increasing and is highest in women from least deprived areas. It is estimated that around 42% of the disease in postmenopausal women could be prevented by increased physical activity and reductions in alcohol intake and body fatness. Breast cancer control endeavours focus on national screening programmes but these do not include communications or interventions for risk reduction This study aimed to assess the feasibility of delivery, indicative effects and acceptability of a lifestyle intervention programme initiated within the NHS Scottish Breast Screening Programme (NHSSBSP). Methods A 1:1 randomised controlled trial (RCT) of the 3 month ActWell programme (focussing on body weight, physical activity and alcohol) versus usual care conducted in two NHSSBSP sites between June 2013 and January 2014. Feasibility assessments included recruitment, retention, and fidelity to protocol. Indicative outcomes were measured at baseline and 3 month follow-up (body weight, waist circumference, eating and alcohol habits and physical activity. At study end, a questionnaire assessed participant satisfaction and qualitative interviews elicited women’s, coaches and radiographers’ experiences. Statistical analysis used Chi squared tests for comparisons in proportions and paired t tests for comparisons of means. Linear regression analyses were performed, adjusted for baseline values, with group allocation as a fixed effect. Results A pre-set recruitment target of 80 women was achieved within 12 weeks and 65 (81%) participants (29 intervention, 36 control) completed 3 month assessments. Mean age was 58 ± 5.6 years, mean BMI was 29.2 ± 7.0 kg/m<superscript>2</superscript> and many (44%) reported a family history of breast cancer. The primary analysis (baseline body weight adjusted) showed a significant between group difference favouring the intervention group of 2.04 kg (95%CI −3.24 kg to −0.85 kg). Significant, favourable between group differences were also detected for BMI, waist circumference, physical activity and sitting time. Women rated the programme highly and 70% said they would recommend it to others. Conclusions Recruitment, retention, indicative results and participant acceptability support the development of a definitive RCT to measure long term effects. [ABSTRACT FROM AUTHOR]
- Subjects :
- BREAST tumor prevention
BEHAVIOR modification
BLOOD pressure
REGULATION of body weight
CHI-squared test
CONFIDENCE intervals
COUNSELING
ALCOHOL drinking
HEALTH behavior
INTERVIEWING
RESEARCH methodology
HEALTH outcome assessment
PAMPHLETS
PATIENT satisfaction
PROBABILITY theory
QUESTIONNAIRES
REGRESSION analysis
RESEARCH funding
TELEPHONES
SAMPLE size (Statistics)
PEDOMETERS
SOCIOECONOMIC factors
THEMATIC analysis
BODY mass index
RANDOMIZED controlled trials
MOTIVATIONAL interviewing
FAMILY history (Medicine)
SEDENTARY lifestyles
PHYSICAL activity
DATA analysis software
EARLY detection of cancer
Subjects
Details
- Language :
- English
- ISSN :
- 14795868
- Volume :
- 11
- Database :
- Complementary Index
- Journal :
- International Journal of Behavioral Nutrition & Physical Activity
- Publication Type :
- Academic Journal
- Accession number :
- 100311255
- Full Text :
- https://doi.org/10.1186/s12966-014-0156-2