Epidemiological study of bone mineral density in 9103 physical examination subjects in Beijing.

Objective To investigate the bone mineral density of 9103 subjects who received physical examination, and to explore the epidemiology of osteoporosis (OP) in Beijing. Methods BMD of the distal one-third of the radius and the ulna of non-dominant forearm in 9103 Han subjects, who received [physical examination in our hospital from March 2012 to July 2012, was detected using DXA (ExA-3000, Osteosys Co., South Korea). The information of all the subjects, including BMD, height, weight, and BMI, were collected and recorded. The results were grouped in a 10-year range. And BMD, T-score, Z-score, incidence, and related influencing factors in each group were analyzed. Results The peak bone mass in males (0.528 ± 0.072) and females (0.451 ± 0.067) in Beijing appeared in 30-39 years old group. Along with the increase of age, BMD in each group decreased. while the incidence of OP increased. BMD in males and females younger than 30 years old was 0.47 ±0.107 and 0.436 ±0.060, respectively. And the incidence of OP in males and females was 21. 88% and 1.33%, respectively. BMD in males and females in 30-39 years old group was 0-528 ±0.072 and 0.451 ±0.067, respectively. And the incidence of OP in males and females was 7.31% and 1.71%, respectively. BMD in males and females in 40-49 years old group was 0.52 ±0.071 and 0.445 ± 0.065, respectively. And the incidence of OP in males and females was 9.88% and 2.3%, respectively. BMD in males and females in 50 - 59 years old group was 0.49 ± 0.076 and 0.396 ± 0.082, respectively. And the incidence of OP in males and females was 20.83% and 18.94%, respectively. BMD in males and females in 60-69 years old group was 0.463 ±0.085 and 0.328 ±0.071, respectively. And the incidence of OP in males and females was 35.49% and 52. 21%, respectively. BMD in males and females in 70-79 years old group was 0.416 ± 0.086 and 0.268 ± 0.072, respectively. And the incidence of OP in males and females was 57.31% and 77.59%, respectively. BMD in males and females over 80 years old was 0.384 ± 0.091 and 0.222 ±0.059, respectively. And the incidence of OP in males and females was 71. 37% and 95. 24%, respectively. The incidence of OP in people with lower BMI was significantly higher than that in people with normal BMI or higher BMI (P < 0.05). Conclusion After the peak bone mass, BMD decreases along with the increase of age and the incidence of OP increases obviously. Meanwhile, the bone mass of postmenopause women decreases obviously, and the incidence of OP is significantly higher than that in men with the same age. It is noteworthy that BMD of young men under 30 years old is not ideal, which may be related to busy work, stressful life, lack for exercise, and unhealthy lifestyle. Measurement of BMD should become the general project in medical examination, which may benefit to the early discovery and active intervention. Meanwhile, we should strengthen the health education in young people, advocate healthy lifestyle, and increase peak bone mass. All may have great significance in preventing osteoporosis. [ABSTRACT FROM AUTHOR]