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Salivary amylase activity of rats fed a low calcium diet.
- Source :
-
Japanese journal of pharmacology [Jpn J Pharmacol] 1998 Nov; Vol. 78 (3), pp. 279-83. - Publication Year :
- 1998
-
Abstract
- Wistar strain rats fed low calcium diets (1, 2, 3, 4, 6 and 8 weeks) exhibited changes in secretory function of whole saliva. In particular, there were changes in salivary flow rate, total salivary protein, amylase enzyme activity, salivary amylase content and the level of cyclic AMP in the parotid gland acinar cell. Although there were no changes for the first 3 weeks, the levels increased at week 4 and decreased at week 6. The wet weight of the parotid gland started to decrease at week 4. These results suggest that when fed low calcium diets for long periods of time, rats develop defective salivary secretion.
- Subjects :
- Amylases metabolism
Animals
Body Weight drug effects
Cyclic AMP metabolism
Male
Organ Size drug effects
Parotid Gland drug effects
Parotid Gland growth & development
Parotid Gland metabolism
Rats
Rats, Wistar
Saliva enzymology
Saliva metabolism
Salivary Proteins and Peptides drug effects
Salivary Proteins and Peptides metabolism
Secretory Rate drug effects
Time Factors
Amylases drug effects
Calcium, Dietary administration & dosage
Saliva drug effects
Subjects
Details
- Language :
- English
- ISSN :
- 0021-5198
- Volume :
- 78
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Japanese journal of pharmacology
- Publication Type :
- Academic Journal
- Accession number :
- 9869261
- Full Text :
- https://doi.org/10.1254/jjp.78.279