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Abnormal or absent beta mRNA in betao Ferrara and gene deletion in delta beta thalassaemia.

Authors :
Ramirez F
O'Donnell JV
Marks PA
Bank A
Musumeci S
SchilirĂ² G
Pizzarelli G
Russo G
Luppis B
Gambino R
Source :
Nature [Nature] 1976 Oct 07; Vol. 263 (5577), pp. 471-5.
Publication Year :
1976

Abstract

In patients with betao thalassaemia from Ferrara, beta globin mRNA sequences are either absent or structurally abnormal while in betao thalassaemia in Catania, beta globin mRNA sequences are present. In deltabeta thalassaemia there is a deletion of beta-like globin genes, while in betao Catania DNA, no beta globin gene deletion is detectable.

Details

Language :
English
ISSN :
0028-0836
Volume :
263
Issue :
5577
Database :
MEDLINE
Journal :
Nature
Publication Type :
Academic Journal
Accession number :
985635
Full Text :
https://doi.org/10.1038/263471a0