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Analysis of postoperative liver function of donors in living-related liver transplantation: comparison of the type of donor hepatectomy.
- Source :
-
Transplantation [Transplantation] 1998 Oct 27; Vol. 66 (8), pp. 1035-9. - Publication Year :
- 1998
-
Abstract
- Background: There is a potentially significant risk to the donor in living-related liver transplantation.<br />Methods: We analyzed surgical risk and stress to 35 donors in living-related liver transplantation with special reference to the types of donor hepatectomy. Donor surgery was performed in one of three ways: (1) lateral segmentectomy without ligation of the middle hepatic vein (MHV) in the remnant liver (group 1, n=21); (2) lateral segmentectomy with ligation of MHV in the remnant liver (group 2, n=6); and (3) left lobectomy with MHV (group 3, n=8).<br />Results: No critical complications were observed in any group. The postoperative enzyme levels in group 2 were significantly higher than those in groups 1 and 3 (P<0.01). Although blood loss was covered by autologous blood transfusion in the first six cases, no banked blood was transfused in any of the cases. Surgical duration was significantly longer and blood loss was significantly greater in group 3 than in group 1 (P<0.05). Follow-up computed tomography showed atrophic changes in segment IV in groups 1 and 2. No remarkable changes were seen in segments V or VIII in any of the three groups.<br />Conclusion: Regardless of the donor hepatectomy procedure, serious complications did nor occur after surgery. Although it should be noted that the type of donor hepatectomy affects postoperative donor liver function, left lateral segmentectomy with ligation of MHV in the remnant liver is a useful method for obtaining liver grafts from living-related donors who have unusual anatomic variations of the hepatic veins.
- Subjects :
- Adult
Atrophy
Child, Preschool
Female
Follow-Up Studies
Hepatectomy methods
Humans
Infant
Liver diagnostic imaging
Liver enzymology
Liver pathology
Male
Organ Size
Postoperative Complications
Postoperative Period
Tomography, X-Ray Computed
Treatment Outcome
Liver physiopathology
Liver Transplantation
Living Donors
Subjects
Details
- Language :
- English
- ISSN :
- 0041-1337
- Volume :
- 66
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Transplantation
- Publication Type :
- Academic Journal
- Accession number :
- 9808488
- Full Text :
- https://doi.org/10.1097/00007890-199810270-00012