Back to Search
Start Over
[The bioavailability of tableted drug forms of the new Russian nootropic preparation nooglutil in rabbits].
- Source :
-
Eksperimental'naia i klinicheskaia farmakologiia [Eksp Klin Farmakol] 1998 Jul-Aug; Vol. 61 (4), pp. 48-50. - Publication Year :
- 1998
-
Abstract
- Comparative study of the main pharmacokinetic characteristics and evaluation of the bioavailability of two experimental tablet forms of the new nootropic nooglutil in relation to the substance of the drug were conducted on rabbits. The nooglutil content in plasma samples was determined by high performance liquid chromatography. Significant advantage of one tablet of the drug containing tween-80 was demonstrated. Bioavailability of this drug form of nooglutil in relation to the substance of the drug was 104.3%.
- Subjects :
- Animals
Biological Availability
Calibration
Capsules
Chromatography, High Pressure Liquid
Chromatography, Liquid
Glutamates administration & dosage
Glutamates blood
Male
Nicotinic Acids administration & dosage
Nicotinic Acids blood
Nootropic Agents administration & dosage
Nootropic Agents blood
Rabbits
Tablets
Time Factors
Glutamates pharmacokinetics
Nicotinic Acids pharmacokinetics
Nootropic Agents pharmacokinetics
Subjects
Details
- Language :
- Russian
- ISSN :
- 0869-2092
- Volume :
- 61
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Eksperimental'naia i klinicheskaia farmakologiia
- Publication Type :
- Academic Journal
- Accession number :
- 9783110