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[The bioavailability of tableted drug forms of the new Russian nootropic preparation nooglutil in rabbits].

Authors :
Chesnokova EA
Sariev AK
Zherdev VP
Kartashov VS
Smirnov LD
Source :
Eksperimental'naia i klinicheskaia farmakologiia [Eksp Klin Farmakol] 1998 Jul-Aug; Vol. 61 (4), pp. 48-50.
Publication Year :
1998

Abstract

Comparative study of the main pharmacokinetic characteristics and evaluation of the bioavailability of two experimental tablet forms of the new nootropic nooglutil in relation to the substance of the drug were conducted on rabbits. The nooglutil content in plasma samples was determined by high performance liquid chromatography. Significant advantage of one tablet of the drug containing tween-80 was demonstrated. Bioavailability of this drug form of nooglutil in relation to the substance of the drug was 104.3%.

Details

Language :
Russian
ISSN :
0869-2092
Volume :
61
Issue :
4
Database :
MEDLINE
Journal :
Eksperimental'naia i klinicheskaia farmakologiia
Publication Type :
Academic Journal
Accession number :
9783110