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[Paraneoplastic intestinal pseudo-obstruction revealing small cell lung carcinoma: "the anti-Hu syndrome"].

Authors :
Cuillerier E
Coffin B
Potet F
Dapoigny M
Flourie B
Coffin JC
Benyahia B
Bitoun A
Messing B
Rambaud JC
Source :
Gastroenterologie clinique et biologique [Gastroenterol Clin Biol] 1998 Mar; Vol. 22 (3), pp. 346-8.
Publication Year :
1998

Abstract

A 67-year-old woman was admitted for intestinal pseudoobstruction associated with peripheral sensitive neuropathy. Jejunal biopsies performed during laparotomy, showed axonal degeneration and lympho-plasmocytic infiltration in myenteric plexus. High titer of seric anti-Hu antibodies suggested a paraneoplastic syndrome. Thoracic CT scan showed mediastinal lymph nodes. Their histological examination confirmed the diagnosis of metastatic small-cell lung carcinoma. Her condition gradually deteriorated despite supportive parenteral nutrition, chemotherapy, steroids and intravenous immunoglobulins. She died 12 months after the onset of symptoms.

Details

Language :
French
ISSN :
0399-8320
Volume :
22
Issue :
3
Database :
MEDLINE
Journal :
Gastroenterologie clinique et biologique
Publication Type :
Academic Journal
Accession number :
9762221