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Cytotoxic sterols from the soft coral Nephthea erecta.
- Source :
-
Journal of natural products [J Nat Prod] 1998 Aug; Vol. 61 (8), pp. 1022-4. - Publication Year :
- 1998
-
Abstract
- Two new cytotoxic sterols, 24-methylcholesta-5,24(28)-diene-3beta, 15beta,19-triol (1) and 24-methylcholesta-5,24(28)-diene-3beta, 19-diol-7-one (2), as well as four cytotoxic sterols, 24-methylcholesta-5,24(28)-diene-3beta,19-diol (3), 24-methylcholesta-5,24(28)-diene-3beta,19-diol-7beta-mono aetate (4), 24-methylcholesta-5,24(28)-diene-3beta,7beta,19-triol (5), and 24-methylcholesta-24(28)-ene-3beta,5alpha,6beta,19-tet raol (6), have been isolated from the soft coral Nephthea erecta. The structures of compounds 1 and 2 were determined by spectral analysis.
- Subjects :
- Animals
Antineoplastic Agents pharmacology
Drug Screening Assays, Antitumor
Humans
Magnetic Resonance Spectroscopy
Mass Spectrometry
Spectrophotometry, Infrared
Spectrophotometry, Ultraviolet
Sterols pharmacology
Tumor Cells, Cultured
Antineoplastic Agents isolation & purification
Cnidaria chemistry
Sterols isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 0163-3864
- Volume :
- 61
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Journal of natural products
- Publication Type :
- Academic Journal
- Accession number :
- 9722490
- Full Text :
- https://doi.org/10.1021/np9800497