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[The effect of anesthesia on kidney scintigraphy in the dog].
- Source :
-
Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere [Tierarztl Prax Ausg K Kleintiere Heimtiere] 1998 Jul; Vol. 26 (4), pp. 259-63. - Publication Year :
- 1998
-
Abstract
- Renal scintigraphy is one of the diagnostic devices in the upper urinary tract. In 24 dogs of different age, sex and breed that--according to the usual laboratory tests--were considered healthy with respect to renal function, a renal scintigraphy with the tubular excreted tracer 99mTc-MAG3 was performed. The dogs were grouped according to three different anaesthetic regimens in order to estimate the influence of anaesthesia--which is necessary for this investigation--onto function of the normal kidney. Eight dogs were scintigraphed twice using different anaesthesia protocols. In group A (n = 22), anaesthesia was performed with a combination of atropine/diazepam/ketamine/xylazine. The reference range determined was for the period of maximal activity accumulation (Tmax) 3.2 +/- 0.8 min and for the elimination half-time (Tmax/2) 6.3 +/- 1.4 min. MAG3-clearance was 7.5 +/- 1.8 ml/min/kg. Group B (n = 5) received thiopental as a continuous intravenous infusion. Tmax was measured with 2.9 +/- 1.1 min, Tmax/2 with 4.7 +/- 1.2 min and the MAG3-clearance was 6.8 +/- 1.6 ml/min/kg. In group C (n = 5), the dogs were given propofol and halothane, and the values determined for Tmax and Tmax/2 were 4.8 +/- 2.7 and 4.8 +/- 1.4 min, respectively. The MAG3-clearance was 10.0 +/- 2.3 ml/min/kg. It is concluded that the anaesthetic regime used has a distinct influence on the reference values.
- Subjects :
- Anesthesia adverse effects
Anesthetics administration & dosage
Anesthetics, Combined administration & dosage
Animals
Atropine administration & dosage
Atropine pharmacology
Diazepam administration & dosage
Diazepam pharmacology
Female
Half-Life
Halothane administration & dosage
Halothane pharmacology
Infusions, Intravenous veterinary
Ketamine administration & dosage
Ketamine pharmacology
Kidney drug effects
Kidney physiology
Male
Propofol administration & dosage
Propofol pharmacology
Radionuclide Imaging
Radiopharmaceuticals
Reference Values
Technetium Tc 99m Mertiatide
Thiopental administration & dosage
Thiopental pharmacology
Xylazine administration & dosage
Xylazine pharmacology
Anesthesia veterinary
Anesthetics pharmacology
Dogs physiology
Kidney diagnostic imaging
Subjects
Details
- Language :
- German
- ISSN :
- 1434-1239
- Volume :
- 26
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
- Publication Type :
- Academic Journal
- Accession number :
- 9710934