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[Oxygen consumption by indirect calorimetry and Fick equation in swine: role of cardiac output].
- Source :
-
Annales francaises d'anesthesie et de reanimation [Ann Fr Anesth Reanim] 1997; Vol. 16 (2), pp. 131-7. - Publication Year :
- 1997
-
Abstract
- Objectives: To compare O2 uptake values measured by indirect calorimetry (VO2R) with Fick-derived values (VO2Fick) over a wide range of VO2 in experimental conditions and to analyze the influence of cardiac output (QC) on the difference between VO2R and VO2Fick.<br />Study Design: Animal study.<br />Material: Nineteen 2.5-month-old, 29.2 +/- 2.8-kg, Large White pigs.<br />Methods: A step-by-step decrease in venous return was obtained either by haemorrhage or progressive inferior vena cava and portal veins clamping. Measurements, of 5 to 7 minutes duration included VO2R (Deltatrac), thermodilution QC and arterial and mixed venous blood O2-content. The VO2 values were compared using Bland and Altman's bias analysis. The relationship between QC values and relative error (ER = [VO2R - VO2Fick]/0.5x[VO2R + VO2Fick] was analyzed using a Spearman rank correlation coefficient.<br />Results: The VO2R and VO2Fick arithmetic mean ranged from 108 to 253 mL.min-1 in 130 measurements with broad limits of agreement between both methods. On average, VO2R values were higher than VO2Fick values by +15 +/- 25 mL.min-1. ER significantly decreased with QC (rs = 0.417; P = 0.0001).<br />Conclusion: VO2R values exceed VO2Fick values. This bias does not occur in the low QC range, presumably owing to artifactual over estimation of thermodilution QC.
- Subjects :
- Animals
Calorimetry, Indirect
Mathematics
Swine
Cardiac Output
Oxygen Consumption
Subjects
Details
- Language :
- French
- ISSN :
- 0750-7658
- Volume :
- 16
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Annales francaises d'anesthesie et de reanimation
- Publication Type :
- Academic Journal
- Accession number :
- 9686074
- Full Text :
- https://doi.org/10.1016/s0750-7658(97)87194-8