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Biochemical and biological analyses of farnesyl-protein transferase inhibitors.

Authors :
Kohl NE
Koblan KS
Omer CA
Oliff A
Gibbs JB
Source :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 1998; Vol. 84, pp. 283-91.
Publication Year :
1998

Abstract

The methods outlined in Subheading 3. provide a logical sequence of assays with which to evaluate the biochemical and biological properties of potential FPTase inhibitors. The clinical predictability of these assays must await the evaluation of one or more of these compounds in humans.

Details

Language :
English
ISSN :
1064-3745
Volume :
84
Database :
MEDLINE
Journal :
Methods in molecular biology (Clifton, N.J.)
Publication Type :
Academic Journal
Accession number :
9666457
Full Text :
https://doi.org/10.1385/0-89603-488-7:283