Back to Search
Start Over
Comparison of bioactive glass synthetic bone graft particles and open debridement in the treatment of human periodontal defects. A clinical study.
- Source :
-
Journal of periodontology [J Periodontol] 1998 Jun; Vol. 69 (6), pp. 698-709. - Publication Year :
- 1998
-
Abstract
- The purpose of this study was to compare the repair response of bioactive glass synthetic bone graft particles and open debridement in the treatment of human periodontal osseous defects. Fifty-nine defects in 16 healthy adults were selected. Each patient had at least 2 sites with attachment loss of at least 6 mm with clinical and radiographic evidence of intrabony or furcation defects. One to 3 months after cause-related therapy (oral hygiene instructions, scaling and root planing), the following measurements were recorded prior to surgery: probing depths, clinical attachment level, and gingival recession. Each defect was surgically exposed and measurements made of the alveolar crest height and base of osseous defect. The test defects were implanted with bioactive glass. The other sites served as unimplanted controls. Flaps were sutured at or close to the presurgical level. Radiographs and soft tissue presurgical measurements were repeated at 6, 9, and 12 months. At 12 months all sites were surgically re-entered to record osseous measurements. At the 12-month evaluation, significantly greater mean probing depth reduction was noted in the bioactive glass group compared to the controls (4.26 mm versus 3.44 mm; P = 0.028). Clinical attachment level gain was significantly improved (P = 0.0004) in the bioactive glass sites (2.96 mm) compared to the control sites (1.54 mm). There was significantly less gingival recession in the bioactive glass sites (1.29 mm) compared to the control sites (1.87 mm). Defect fill was significantly greater in the bioactive glass sites (3.28 mm) compared to the control sites (1.45 mm). Defect depth reduction was significantly greater in the bioactive glass sites (4.36 mm) compared to the control sites (3.15 mm). In conclusion, bioactive glass showed significant improvement in clinical parameters compared to open flap debridement.
- Subjects :
- Adult
Alveolar Bone Loss diagnostic imaging
Alveolar Bone Loss surgery
Alveolar Process diagnostic imaging
Alveolar Process pathology
Dental Plaque Index
Dental Scaling
Female
Follow-Up Studies
Furcation Defects diagnostic imaging
Furcation Defects surgery
Gingival Recession surgery
Humans
Male
Oral Hygiene
Patient Education as Topic
Periodontal Attachment Loss diagnostic imaging
Periodontal Attachment Loss surgery
Periodontal Diseases diagnostic imaging
Periodontal Index
Periodontal Pocket diagnostic imaging
Periodontal Pocket surgery
Radiography
Root Planing
Surgical Flaps
Tooth Mobility pathology
Biocompatible Materials therapeutic use
Bone Substitutes therapeutic use
Debridement
Glass
Periodontal Diseases surgery
Subjects
Details
- Language :
- English
- ISSN :
- 0022-3492
- Volume :
- 69
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Journal of periodontology
- Publication Type :
- Academic Journal
- Accession number :
- 9660339
- Full Text :
- https://doi.org/10.1902/jop.1998.69.6.698