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Spanish and African contribution to the genetic pool of the Canary islanders: data from GM and KM haplotypes and RFLPs in the immunoglobulin IGHG loci.
- Source :
-
Annals of human genetics [Ann Hum Genet] 1998 Jan; Vol. 62 (Pt 1), pp. 33-45. - Publication Year :
- 1998
-
Abstract
- Data on the GM and KM haplotypes and RFLPs in the immunoglobulin IGHG loci are reported intending to evaluate the genetic contribution of the different populations (Europeans and Africans) who settled Tenerife Island. The GM and KM allotypic systems reveal an estimated European genetic admixture of 88%. The only possible African contribution is the presence of the GM*1,17;...;5* haplotype (2.5%), but no other traces of Black African characteristic haplotypes are found. Although new RFLP haplotypes are described, DNA variation is similar to that reported in Caucasoids with a marked absence of restriction fragments characteristic of Black Africans.
- Subjects :
- Africa
Atlantic Islands
Deoxyribonuclease BamHI
Deoxyribonucleases, Type II Site-Specific
Haplotypes
Humans
Immunoglobulin Constant Regions genetics
Immunoglobulin Gm Allotypes genetics
Spain ethnology
Black People genetics
Genes, Immunoglobulin
Immunoglobulin Allotypes genetics
Immunoglobulin Heavy Chains genetics
Polymorphism, Restriction Fragment Length
White People genetics
Subjects
Details
- Language :
- English
- ISSN :
- 0003-4800
- Volume :
- 62
- Issue :
- Pt 1
- Database :
- MEDLINE
- Journal :
- Annals of human genetics
- Publication Type :
- Academic Journal
- Accession number :
- 9659976
- Full Text :
- https://doi.org/10.1046/j.1469-1809.1998.6210033.x