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The effect of herbal extracts in an experimental mouthrinse on established plaque and gingivitis.
- Source :
-
Journal of clinical periodontology [J Clin Periodontol] 1998 May; Vol. 25 (5), pp. 399-403. - Publication Year :
- 1998
-
Abstract
- The purpose of the present study was to establish in vitro the inhibiting effect of a herbal extract mixture on a selected number of micro-organisms and to test in vivo the effect of a mouthwash containing 6.3 mg/ml herbal extract mixture on plaque and gingivitis as compared to a minus active control mouthrinse. The herbal extract was a mixture of: Juniperus communis (juniper), Urtica dioca (nettle), Achillaea millefolium (yarrow); 1:1:1. In the study, in-vitro, the effect of pure herbal extract mixture on acid production of Streptococcus mutans was tested and the minimum inhibitory concentrations (MIC) of the following micro-organisms were tested: Streptococcus mutans, Streptococcus mitis, Actynomyces viscosus, Actynomyces naeslundii, Actinobacillus actinomycetemcomitans, Prevotella intermedia, Campylobacter rectus, Fusobacterium nucleatum, Veillonella parvula. The MIC-values for A. viscosus and P. gingivalis were 100 mg/ml. The MIC-values for A. naeslundii and A. actinomycetemcomitans were considerably lower (10 mg/ml). S. mitis was the most susceptible of the tested organisms to the extract with a MIC value of 1 mg/ml. S. mutans, C. rectus, V. parvula, and F. nucleatum were not influenced by the extracts. No inhibitory effect of the 6.3 mg/ml herbal extract mixture was observed on the acid production of S. mutans. For the study in-vivo, 45 volunteers were selected on the basis of having moderate gingival inflammation. As efficacy parameters the plaque index, modified gingival index and angulated bleeding index were assessed. The subjects were randomly divided among 3 experimental groups (2x test and 1 'minus active' control). The participants were requested to rinse with 10 ml of mouthwash twice a day for a period of three months. After 6 weeks and 3 months, the same clinical indices as at baseline were recorded. The results show no difference between the two test groups and the control group. In conclusion, the results of the present study have shown that the mixture of the 3 herbal extracts, Juniperus communis, Urtica dioca and Achillaea millefolium when used in a mouthrinse has no effect on plaque growth and gingival health.
- Subjects :
- Actinomyces drug effects
Actinomyces viscosus drug effects
Aggregatibacter actinomycetemcomitans drug effects
Anti-Bacterial Agents pharmacology
Asteraceae
Campylobacter drug effects
Follow-Up Studies
Fusobacterium nucleatum drug effects
Gingival Hemorrhage prevention & control
Humans
In Vitro Techniques
Juniperus
Mouthwashes pharmacology
Periodontal Index
Plant Extracts pharmacology
Prevotella intermedia drug effects
Streptococcus drug effects
Streptococcus mutans drug effects
Veillonella drug effects
Anti-Bacterial Agents therapeutic use
Dental Plaque prevention & control
Gingivitis prevention & control
Magnoliopsida
Mouthwashes therapeutic use
Plant Extracts therapeutic use
Plants, Medicinal
Subjects
Details
- Language :
- English
- ISSN :
- 0303-6979
- Volume :
- 25
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Journal of clinical periodontology
- Publication Type :
- Academic Journal
- Accession number :
- 9650877
- Full Text :
- https://doi.org/10.1111/j.1600-051x.1998.tb02462.x