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[Specific stimulation of the lymphocyte blast transformation reaction in patients with rheumatism under conditions of exposure to delagil, mephenaminic acid and amidopyrine].

Authors :
Ponomareva AG
Sachkov VI
Source :
Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 1976 (3), pp. 135-8.
Publication Year :
1976

Abstract

Antirheumatic preparations chiefly inhibited (in vitro) the specific microbial stimulation of the reaction of blast transformation of lymphocytes (RBL) in the patients with torpid rheumocarditis caused by addition of streptococcus nucleoproteid into the medium. Specifically stimulated RBL became intensified in healthy donors on addition to the culture medium of amidopyrin and mephenaminic acid; as to delagil, it depressed the specifically stimulated RBL both in healthy donors and in patients.

Details

Language :
Russian
ISSN :
0372-9311
Issue :
3
Database :
MEDLINE
Journal :
Zhurnal mikrobiologii, epidemiologii i immunobiologii
Publication Type :
Academic Journal
Accession number :
961259