Variant in the regulatory subunit of phosphatidylinositol 3-kinase (p85alpha): preliminary evidence indicates a potential role of this variant in the acute insulin response and type 2 diabetes in Pima women.

Subjects

Subjects :

Adult
Arizona
Blood Glucose drug effects
Blood Glucose metabolism
Diabetes Mellitus, Type 2 epidemiology
Female
Genotype
Glucose metabolism
Glucose Tolerance Test
Humans
Insulin blood
Macromolecular Substances
Phosphatidylinositol 3-Kinases chemistry
Polymorphism, Genetic
Prevalence
Diabetes Mellitus, Type 2 enzymology
Diabetes Mellitus, Type 2 genetics
Genetic Variation
Indians, North American genetics
Insulin pharmacology
Insulin Resistance genetics
Phosphatidylinositol 3-Kinases genetics
Point Mutation

Details

Language :

English

ISSN :

0012-1797

Volume :

47

Issue :

6

Database :

MEDLINE

Journal :

Diabetes

Publication Type :

Academic Journal

Accession number :

9604878

Full Text :

https://doi.org/10.2337/diabetes.47.6.973