Outcome of transfusion of K:11 erythrocytes in a patient with anti-K11 antibody.

Background and Objectives: The clinical significance of anti-K11 in red cell transfusion therapy is unknown. We report the outcome of transfusion of K:11 erythrocytes into a patient with a known anti-K11 antibody.
Materials and Methods: The patient was monitored clinically following transfusion of 11 units of K:11 erythrocytes. A red cell survival study with K:11 erythrocytes and a monocyte monolayer assay (MMA) were performed.
Results: No adverse clinical outcome was detected. The red cell survival study showed normal survival of K:11 erythrocytes, and the MMA showed no increase in reactive monocytes.
Conclusion: These findings suggest that K:11 red cells can safely be transfused to individuals with anti-K11 antibody.