[Dynamics of spontaneous beating of cardiomyocytes in vitro depend on the number of involved cells].

The dynamics of cardiomyocyte spontaneous beatings with fractal dimension calculation was studied. It was shown that isolated single cardiomyocyte beats stochastically, but when a number of cells synchronized a significant changes in the dynamics appear: deterministic chaos could be detected. Several reasons are discussed as a possible explanation of such a behavior: the effect of system volume increasing and specific influence of gap-junctions on the rhythm formation.