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[Ocular myasthenia: clinical course and strategies for treatment].
- Source :
-
Revista de neurologia [Rev Neurol] 1998 Mar; Vol. 26 (151), pp. 398-400. - Publication Year :
- 1998
-
Abstract
- Introduction: Ocular myasthenia gravis is a localized form of myasthenia in which only the extra-ocular muscles are clinically affected, namely the levator palpebrae superioris and orbicularis oculi. Two years after onset of the ocular condition, it became generalized in 44-53% of the patients.<br />Objective: 1. To describe the clinical features, diagnostic characteristics and clinical course of seven patients who fulfilled the criteria for diagnosis of ocular myasthenia and in whom the condition did not become generalized: 2. Review recent papers on this. Material and methods. We studied seven patients (two men and two women) diagnosed as having ocular myasthenia gravis, and followed them up for at least three years.<br />Results: The average age was 56.5. The clinical findings were of ptosis of the eyelids and diplopia. All seven patients were treated with pyridostigmine. In six cases prednisone was also given and in one patient thymectomy was done. There was a satisfactory result in all cases.<br />Conclusions: The basic treatment of ocular myasthenia is with anticholinesterases and corticosteroids. Occasionally other immunosuppressives may be required. Prednisone seems to reduce the number of patients who go on to develop the generalized form.
- Subjects :
- Adult
Aged
Blepharoptosis complications
Diplopia complications
Female
Follow-Up Studies
Humans
Male
Middle Aged
Prognosis
Thymectomy
Anti-Inflammatory Agents therapeutic use
Cholinesterase Inhibitors therapeutic use
Myasthenia Gravis complications
Myasthenia Gravis drug therapy
Ocular Motility Disorders etiology
Ocular Motility Disorders therapy
Prednisone therapeutic use
Pyridostigmine Bromide therapeutic use
Subjects
Details
- Language :
- Spanish; Castilian
- ISSN :
- 0210-0010
- Volume :
- 26
- Issue :
- 151
- Database :
- MEDLINE
- Journal :
- Revista de neurologia
- Publication Type :
- Academic Journal
- Accession number :
- 9585951