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[Preventive use of antibiotics in neonatal surgery].
- Source :
-
Anales espanoles de pediatria [An Esp Pediatr] 1997 Dec; Vol. 47 (6), pp. 621-6. - Publication Year :
- 1997
-
Abstract
- Objective: The objective of this study was to determine the incidence of surgical wound infection and the impact of this on the implementation of an antibiotic protocol according to the type of surgery and the prevailing endogenous flora in our neonatology unit.<br />Patients and Methods: Patients' charts were retrospectively reviewed in order to assess the effectiveness of a protocol of surgical prophylaxis, comparing the incidence of postsurgical wound infection in two periods of time. Surgical interventions were classified according to the period of the study in which they were performed, before (period A) and after (period B) the protocol was undertaken. In addition, if the antibiotics administered fit or not those indicated in the protocol, it was classified as correct or not.<br />Results: A total of 31 (37%) of the interventions were performed in period A, whereas 53 (63%) were carried out in period B. No statistically significant differences were found between periods with regard to the proportion of infections 925.8% vs 15%). When prophylactic antibiotics were administered correctly, infection occurred in 10.2%, as compared to 31.4% when they did not fit the protocol (p < 0.05). The duration of the antibiotics was longer in period A, in infected wounds and when prophylaxis was not correct.<br />Conclusions: The correct adjustment to the protocol significantly decreases the incidence of wound infections, as well as the duration of antibiotic use. An appropriate policy of antibiotic prophylaxis in surgery is advantageous in terms of economic cost and might prevent antibiotic resistance and avoid unnecessary toxicity.
- Subjects :
- Clinical Protocols
Female
Humans
Infant, Newborn
Male
Retrospective Studies
Surgical Procedures, Operative economics
Surgical Wound Infection diagnosis
Surgical Wound Infection microbiology
Antibiotic Prophylaxis
Surgical Procedures, Operative standards
Surgical Wound Infection prevention & control
Subjects
Details
- Language :
- Spanish; Castilian
- ISSN :
- 0302-4342
- Volume :
- 47
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Anales espanoles de pediatria
- Publication Type :
- Academic Journal
- Accession number :
- 9580070