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Highly resolved chemical imaging of living cells by using synchrotron infrared microspectrometry.
- Source :
-
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1998 Apr 28; Vol. 95 (9), pp. 4837-40. - Publication Year :
- 1998
-
Abstract
- Using synchrotron radiation as an ultra-bright infrared source, we have been able to map the distributions of functional groups such as proteins, lipids, and nucleic acids inside a single living cell with a spatial resolution of a few microns. In particular, we have mapped the changes in the lipid and protein distributions in both the final stages of cell division and also during necrosis.
Details
- Language :
- English
- ISSN :
- 0027-8424
- Volume :
- 95
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Proceedings of the National Academy of Sciences of the United States of America
- Publication Type :
- Academic Journal
- Accession number :
- 9560189
- Full Text :
- https://doi.org/10.1073/pnas.95.9.4837