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Highly resolved chemical imaging of living cells by using synchrotron infrared microspectrometry.

Authors :
Jamin N
Dumas P
Moncuit J
Fridman WH
Teillaud JL
Carr GL
Williams GP
Source :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1998 Apr 28; Vol. 95 (9), pp. 4837-40.
Publication Year :
1998

Abstract

Using synchrotron radiation as an ultra-bright infrared source, we have been able to map the distributions of functional groups such as proteins, lipids, and nucleic acids inside a single living cell with a spatial resolution of a few microns. In particular, we have mapped the changes in the lipid and protein distributions in both the final stages of cell division and also during necrosis.

Details

Language :
English
ISSN :
0027-8424
Volume :
95
Issue :
9
Database :
MEDLINE
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
9560189
Full Text :
https://doi.org/10.1073/pnas.95.9.4837