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Sleep in patients with chronic obstructive pulmonary disease.
- Source :
-
Clinics in chest medicine [Clin Chest Med] 1998 Mar; Vol. 19 (1), pp. 115-25. - Publication Year :
- 1998
-
Abstract
- Patients with chronic obstructive pulmonary disease (COPD) become hypoxemic during sleep, particularly during rapid eye movement (REM) sleep. Those who are most hypoxemic when awake experience the most severe hypoxemia during sleep. The major cause of REM hypoxemia is hypoventilation, with additional contributions from alteration in ventilation/perfusion matching and functional residual capacity (FRC) reduction. REM hypoxemia probably contributes to the development of pulmonary hypertension and polycythemia and may predispose to cardiac arrhythmias in some patients. The most effective form of therapy is nocturnal oxygen therapy, but the indications for the use of nocturnal oxygen therapy are entirely based on daytime oxygenation levels. Routine polysomnography is not indicated in patients with COPD but should be performed in patients who have symptoms suggestive of coexisting sleep apnea/ hypopnea syndrome.
- Subjects :
- Clinical Trials as Topic
Female
Functional Residual Capacity
Hemodynamics physiology
Humans
Hypoventilation diagnosis
Hypoventilation etiology
Hypoventilation therapy
Lung Diseases, Obstructive diagnosis
Lung Diseases, Obstructive therapy
Male
Oxygen therapeutic use
Positive-Pressure Respiration
Prognosis
Respiratory System Agents therapeutic use
Sleep Apnea Syndromes diagnosis
Sleep Wake Disorders diagnosis
Sleep Wake Disorders etiology
Sleep Wake Disorders physiopathology
Lung Diseases, Obstructive complications
Sleep Apnea Syndromes etiology
Sleep Apnea Syndromes therapy
Subjects
Details
- Language :
- English
- ISSN :
- 0272-5231
- Volume :
- 19
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Clinics in chest medicine
- Publication Type :
- Academic Journal
- Accession number :
- 9554222
- Full Text :
- https://doi.org/10.1016/s0272-5231(05)70436-6