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Response of plasma testosterone, urinary 17-oxosteroids, oestrogens, and androsterone plus aetiocholanolone to human chorionic gonadotrophin in dexamethasone-suppressed men.
- Source :
-
Clinical endocrinology [Clin Endocrinol (Oxf)] 1976 May; Vol. 5 (3), pp. 235-43. - Publication Year :
- 1976
-
Abstract
- The administration of human chorionic gonadotrophin (HCG) to dexamethasone-suppressed men caused parallel changes in the concentration of plasma testosterone and in the urinary output of androsterone+aetiocholanolone, total 17-oxosteroids and oestrogens. Discrepant results occurred in only four of the thirty-seven men tested. With these exceptions, the response to HCG could by followed as well by measuring androsterone+aetiocholanolone, 17-oxosteroid or oestrogen excretion rates as by following plasma testosterone levels. The most sensitive index of response was the rate of appearance of oestrogens in urine, and the next that of androsterone+aetiocholanolone.
- Subjects :
- Adolescent
Adrenal Glands drug effects
Adult
Depression, Chemical
Humans
Hypogonadism diagnosis
Male
Middle Aged
Testis drug effects
17-Ketosteroids urine
Adrenal Glands metabolism
Androsterone urine
Chorionic Gonadotropin
Dexamethasone pharmacology
Estrogens urine
Etiocholanolone urine
Hypogonadism physiopathology
Testis metabolism
Testosterone blood
Subjects
Details
- Language :
- English
- ISSN :
- 0300-0664
- Volume :
- 5
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Clinical endocrinology
- Publication Type :
- Academic Journal
- Accession number :
- 954218
- Full Text :
- https://doi.org/10.1111/j.1365-2265.1976.tb01949.x