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[Systemic analysis of neuroimmune mechanisms of memory].
- Source :
-
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova [Ross Fiziol Zh Im I M Sechenova] 1997 Nov-Dec; Vol. 83 (11-12), pp. 19-28. - Publication Year :
- 1997
-
Abstract
- Administration of IL-1 beta and 125-129 fragment of alpha 2-interferon improved learning and retention of active avoidance behaviour in memory in rats. It also improved the correlation between intersignal runs and success of the avoidance behaviour learning. The data obtained suggest that an activation of the intersignal retention process is one of the mechanisms of the immunomodulators effect on learning and memory.
- Subjects :
- Animals
Avoidance Learning physiology
Conditioning, Psychological drug effects
Escape Reaction physiology
Exploratory Behavior drug effects
Interferon-alpha
Male
Neuroimmunomodulation physiology
Rats
Rats, Wistar
Reaction Time drug effects
Recombinant Proteins
Systems Theory
Vocalization, Animal drug effects
Adjuvants, Immunologic pharmacology
Avoidance Learning drug effects
Escape Reaction drug effects
Interferon Type I pharmacology
Interleukin-1 pharmacology
Memory physiology
Neuroimmunomodulation drug effects
Peptide Fragments pharmacology
Subjects
Details
- Language :
- Russian
- ISSN :
- 0869-8139
- Volume :
- 83
- Issue :
- 11-12
- Database :
- MEDLINE
- Journal :
- Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova
- Publication Type :
- Academic Journal
- Accession number :
- 9541953