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[The predictive signs of multivessel coronary disease in echocardiography with dobutamine].
- Source :
-
Revista espanola de cardiologia [Rev Esp Cardiol] 1997 Nov; Vol. 50 (11), pp. 772-7. - Publication Year :
- 1997
-
Abstract
- Aims: To assess the ability of dobutamine echocardiography to detect multivessel coronary artery disease and to determine predictive factors for multivessel disease with or without beta-blockers.<br />Patients and Methods: A total of 101 patients underwent dobutamine stress echocardiography and coronary angiography (evaluation of chest pain 76, extent of coronary disease after myocardial infarction 19, other indications 6).<br />Results: Ten patients in whom the test was prematurely terminated were excluded. Out of 91 patients who underwent dobutamine echocardiography, 54 patients had multivessel disease (sensitivity of dobutamine test 93%, specificity 46%). Heart rate at the maximum dose of dobutamine or atropine was 88 +/- 21 beats/min for multivessel diseases and 104 +/- 21 beats/min without multivessel disease (p < 0.001). A cut-off value < 94 beats/min discriminated patients at risk for multivessel disease. After adjusting for treatment with beta-blockers, heart rate < 94 beats/min, ECG signs of ischemia, and abnormalities on baseline echocardiogram with remote asynergies during dobutamine testing were independent predictors of multivessel disease in the multivariate analysis (probability > 90% when at least two factors were present).<br />Conclusion: A heart rate < 94 beats/min at peak dose of dobutamine or after atropine, ECG signs of ischemia, and the presence of abnormalities on echocardiogram at rest with remote asynergies during dobutamine stress testing were independent predictive factors of multivessel coronary artery disease.
- Subjects :
- Adult
Aged
Coronary Angiography
Echocardiography statistics & numerical data
Evaluation Studies as Topic
Exercise Test methods
Exercise Test statistics & numerical data
Female
Humans
Male
Middle Aged
Prognosis
Sensitivity and Specificity
Cardiotonic Agents administration & dosage
Coronary Disease diagnostic imaging
Dobutamine administration & dosage
Echocardiography methods
Subjects
Details
- Language :
- Spanish; Castilian
- ISSN :
- 0300-8932
- Volume :
- 50
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Revista espanola de cardiologia
- Publication Type :
- Academic Journal
- Accession number :
- 9424700
- Full Text :
- https://doi.org/10.1016/s0300-8932(97)74679-7