[The criteria of cardiac muscle tissue viability under experimental and clinical conditions].

Comparative analysis of cardiac muscular tissue reactivity in myocardial hypertrophy development in experimental and clinical conditions was performed. Stereotyped reactions to overload were distinguished at intracellular, cellular and tissue levels. Cardiac muscular tissue vital activity was estimated through criteria of "chronos", "morphos", "quantum" and "turnover". It was shown that disruption of genetically determined correlation between processes of proliferation, differentiation and death of cardiomyocytes was a common regularity of cardiomyogenesis in formation of myocardial hypertrophy.