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A synthesis of 7alpha-hydroxyandrost-4-ene-3,17-dione.
- Source :
-
Steroids [Steroids] 1976 May; Vol. 27 (5), pp. 603-8. - Publication Year :
- 1976
-
Abstract
- The first convenient chemical synthesis of 7alpha-hydroxyandrost-4-ene-3,17-dione is reported. Androsta-4,6-diene3, 17-dione was converted into its 6alpha, 7alpha-epoxy-derivative; reduction of the epoxide with aluminum amalgam gave 7alpha-hydroxyandrost-4-ene-3,17-dione. This reducing agent is more efficient than chromous acetate for the purpose.
Details
- Language :
- English
- ISSN :
- 0039-128X
- Volume :
- 27
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Steroids
- Publication Type :
- Academic Journal
- Accession number :
- 941180
- Full Text :
- https://doi.org/10.1016/s0039-128x(76)90096-9