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Longitudinal study of Aspergillus fumigatus strains isolated from cystic fibrosis patients.
- Source :
-
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology [Eur J Clin Microbiol Infect Dis] 1997 Oct; Vol. 16 (10), pp. 747-50. - Publication Year :
- 1997
-
Abstract
- The colonization over time of cystic fibrosis patients by Aspergillus fumigatus was investigated using a DNA fingerprinting method. Aspergillus fumigatus isolates collected sequentially for more than one year from six patients with cystic fibrosis were typed by Southern blot hybridization with a repetitive DNA sequence. Each cystic fibrosis patient harbored several strains of Aspergillus fumigatus that were isolated recurrently over time. Isolates collected from a cystic fibrosis patient with aspergilloma displayed the same genotype, suggesting that the infection was due to a single strain. Continuous isolation of the same genotype in another cystic fibrosis patient, however, was not correlated clinically with an Aspergillus infection.
- Subjects :
- Adolescent
Aspergillosis prevention & control
Aspergillus fumigatus genetics
Child
Child, Preschool
DNA Fingerprinting
Female
Humans
Longitudinal Studies
Male
Molecular Epidemiology
Recurrence
Time Factors
Aspergillosis epidemiology
Aspergillosis genetics
Aspergillus fumigatus isolation & purification
Cystic Fibrosis complications
DNA, Fungal analysis
Subjects
Details
- Language :
- English
- ISSN :
- 0934-9723
- Volume :
- 16
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
- Publication Type :
- Academic Journal
- Accession number :
- 9405946
- Full Text :
- https://doi.org/10.1007/BF01709257