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[High pressure liquid-liquid chromatography: correlation between retention times and biological activity of 1,3,5-triazine derivatives].

Authors :
Vitali T
Gaetani E
Laureri CF
Branca C
Source :
Il Farmaco; edizione scientifica [Farmaco Sci] 1976 Jan; Vol. 31 (1), pp. 58-65.
Publication Year :
1976

Abstract

An investigation has been made of the possibility of using the retention times t obtained by reversed phase high pressure liquid-liquid chromatography in the study of quantitative structure-activity relatiionships. Taking as an example a group of herbicides which inhibit the Hill reaction, it was found that log t is additive and can be used as the hydrophobic parameter in regression analyses. The characteristics, advantages and possible developments of the method are discussed and the analytical interest is highlighted.

Details

Language :
Italian
ISSN :
0430-0920
Volume :
31
Issue :
1
Database :
MEDLINE
Journal :
Il Farmaco; edizione scientifica
Publication Type :
Academic Journal
Accession number :
939320