[Results of controlled tests of an experimental recombinant live vaccine against hepatitis B].

Authors :: Ikoev VN
Gorbunov MA
Bektimirov TA
Noskova AV
Perekrest VV
Source :: Voprosy virusologii [Vopr Virusol] 1997 May-Jun; Vol. 42 (3), pp. 135-7.
Publication Year :: 1997
Abstract: Experimental recombinant vaccine against hepatitis B Revacc B based on vaccinia virus has been tried. The preparation was weakly reactogenic but did not induce the production of anti-HBasAg antibodies. On the other hand, recombinant vaccine against hepatitis B Engerix B, used in a blind experiment as the agent of comparison, induced the production of anti-HBs in 91% of vaccinees.

Subjects :: Adolescent
Adult
Antibodies, Viral biosynthesis
Controlled Clinical Trials as Topic
Hepatitis B Surface Antigens immunology
Humans
Hepatitis B Vaccines therapeutic use
Vaccines, Synthetic therapeutic use

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