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[Correlation between the tumor marker Pro-GRP and prognosis in patients with small-cell lung cancer].
- Source :
-
Nihon Kyobu Shikkan Gakkai zasshi [Nihon Kyobu Shikkan Gakkai Zasshi] 1997 Jun; Vol. 35 (6), pp. 616-21. - Publication Year :
- 1997
-
Abstract
- We studied 90 patients with small-cell lung cancer in whom levels of Pro-GRP were abnormally high before therapy. Changes in the serum Pro-GRP level have been said to correlate strongly with therapeutic responses in patients with small-cell lung cancer. We found that changes in the serum Pro-GRP level (half-life > or = 30 vs < 30 days) were a significant prognostic factor. Multivariate analysis showed that in these patients the Pro-GRP level after therapy, Performance Status, and age were independent prognostic factors.
- Subjects :
- Adult
Aged
Aged, 80 and over
Carcinoma, Small Cell mortality
Carcinoma, Small Cell therapy
Female
Humans
Lung Neoplasms mortality
Lung Neoplasms therapy
Male
Middle Aged
Prognosis
Survival Rate
Biomarkers, Tumor blood
Carcinoma, Small Cell blood
Gastrin-Releasing Peptide blood
Lung Neoplasms blood
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0301-1542
- Volume :
- 35
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Nihon Kyobu Shikkan Gakkai zasshi
- Publication Type :
- Academic Journal
- Accession number :
- 9294294