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Post-traumatic pleural effusion: demonstration of local complement consumption.

Post-traumatic pleural effusion: demonstration of local complement consumption.

Authors :
de Blay F
Aykut-Baturalp A
Goetz J
Purohit A
Perez-Infante A
Hauptmann G
Pauli G
Source :
Respiratory medicine [Respir Med] 1997 Jul; Vol. 91 (6), pp. 373-5.
Publication Year :
1997

Abstract

The present case report describes a 27-year-old patient who presented with post-traumatic pleural effusion. Analysis of the pleural fluid showed hypereosinophilia (990 mm-3), a decreased level of total complement, and decreased levels of C3 and C4 fractions (less than 50% of normal serum levels), indicating a local consumption mechanism for complement. Complement serum levels (CH50, C3, C4) were normal. All other aetiologic possibilities were eliminated. This case suggests that the immunopathological mechanism of post-traumatic pleural effusion may involve activation of the classical pathway of complement and a recruitment of inflammatory cells such as eosinophils.

Details

Language :
English
ISSN :
0954-6111
Volume :
91
Issue :
6
Database :
MEDLINE
Journal :
Respiratory medicine
Publication Type :
Academic Journal
Accession number :
9282241
Full Text :
https://doi.org/10.1016/s0954-6111(97)90065-2